SeriesLock™ NPT 100 Quick Disconnect Couplings & Inserts

A unique aseptic Spring-Free Flow Path® quick-connect fitting allows a larger volume of fluid to pass through it at lower line pressures. This optimized flow reduces restriction, turbidity, foaming, and bubbles. Recessed mating features protect contact surfaces and prolong the life of the O-rings helping to ensure a better seal. The audible click upon connection and the safety slide release are both features to help minimize accidental disconnects. Three body sizes in Small, Medium, and Large are available to accommodate a variety of connection sizes for NPT thread adapters. Additional sizes, materials, flow paths, and end connections available; contact us for a quote.

  • Natural Kynar® (PVDF), Glass Filled Black Nylon (GFBN), Polypropylene (PP), or Polysulfone (PS)
  • PP, PS & PVDF have silicone O-ring & GFBN has Viton™; 302 stainless steel spring
  • Spring-Free Flow Path® fittings – valved; Superior single barb technology
  • Lubricant: biocompatible & inert PFPE
  • Slide button & main latch: CrystalVu™ PMP copolymer
  • Spillage < 0.05cc per disconnect (small & medium) & < 0.1cc per disconnect (large)
  • Sterilization: EtO, Gamma & E-Beam, Autoclavable
  • Working pressure: vacuum to 90 psi, 6.9 bar
  • Temp. range: GFBN (32°F to 450°F), PP (32°F to 160°F), PVDF (32°F to 250°F), PS (-40°F to 282°F)
  • USP Class VI & ISO10993 Compliant (PVDF & Polypropylene)
Item # Description Catalog Pg. Price Add to Cart
1/8" NPT x 1/8" Tubing Equivalent Natural Kynar® Female SeriesLock™ Valved Coupling - Small
Item 63375
21.89/Each
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21.89/Each
1/8" NPT x 3/16" Tubing Equivalent Natural Kynar® Female SeriesLock™ Valved Coupling - Small
Item 63376
21.89/Each
Save 5% when you buy 5+
Save 10% when you buy 10+
Save 15% when you buy 30+
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21.89/Each
1/4" NPT x 1/4" Tubing Equivalent Natural Kynar® Female SeriesLock™ Valved Coupling - Medium
Item 63377
23.21/Each
Save 5% when you buy 5+
Save 10% when you buy 10+
Save 15% when you buy 30+
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23.21/Each
1/4" NPT x 3/8" Tubing Equivalent Natural Kynar® Female SeriesLock™ Valved Coupling - Medium
Item 63378
23.21/Each
Save 5% when you buy 5+
Save 10% when you buy 10+
Save 15% when you buy 30+
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23.21/Each
3/8" NPT x 1/4" Tubing Equivalent Natural Kynar® Female SeriesLock™ Valved Coupling - Medium
Item 63379
23.78/Each
Save 5% when you buy 5+
Save 10% when you buy 10+
Save 15% when you buy 30+
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23.78/Each
3/8" NPT x 3/8" Tubing Equivalent Natural Kynar® Female SeriesLock™ Valved Coupling - Medium
Item 63380
23.21/Each
Save 5% when you buy 5+
Save 10% when you buy 10+
Save 15% when you buy 30+
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23.21/Each
1/2" NPT x 1/2" Tubing Equivalent Natural Kynar® Female SeriesLock™ Valved Coupling - Large
Item 63381
29.53/Each
Save 5% when you buy 5+
Save 10% when you buy 10+
Save 15% when you buy 30+
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29.53/Each
1/2" NPT x 3/4" Tubing Equivalent Natural Kynar® Female SeriesLock™ Valved Coupling - Large
Item 63382
29.53/Each
Save 5% when you buy 5+
Save 10% when you buy 10+
Save 15% when you buy 30+
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29.53/Each
1/8" NPT x 1/8" Tubing Equivalent Natural Kynar® Male SeriesLock™ Valved Insert - Small
Item 63383
15.42/Each
Save 5% when you buy 5+
Save 10% when you buy 10+
Save 15% when you buy 30+
Internet Only
15.42/Each
1/8" NPT x 3/16" Tubing Equivalent Natural Kynar® Male SeriesLock™ Valved Insert - Small
Item 63384
15.42/Each
Save 5% when you buy 5+
Save 10% when you buy 10+
Save 15% when you buy 30+
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15.42/Each
1/4" NPT x 1/4" Tubing Equivalent Natural Kynar® Male SeriesLock™ Valved Insert - Medium
Item 63385
16.17/Each
Save 5% when you buy 5+
Save 10% when you buy 10+
Save 15% when you buy 30+
Internet Only
16.17/Each
1/4" NPT x 3/8" Tubing Equivalent Natural Kynar® Male SeriesLock™ Valved Insert - Medium
Item 63386
16.17/Each
Save 5% when you buy 5+
Save 10% when you buy 10+
Save 15% when you buy 30+
Internet Only
16.17/Each
3/8" NPT x 1/4" Tubing Equivalent Natural Kynar® Male SeriesLock™ Valved Insert - Medium
Item 63387
16.17/Each
Save 5% when you buy 5+
Save 10% when you buy 10+
Save 15% when you buy 30+
Internet Only
16.17/Each
3/8" NPT x 3/8" Tubing Equivalent Natural Kynar® Male SeriesLock™ Valved Insert - Medium
Item 63388
16.17/Each
Save 5% when you buy 5+
Save 10% when you buy 10+
Save 15% when you buy 30+
Internet Only
16.17/Each
1/2" NPT x 1/2" Tubing Equivalent Natural Kynar® Male SeriesLock™ Valved Insert - Large
Item 63389
21.7/Each
Save 5% when you buy 5+
Save 10% when you buy 10+
Save 15% when you buy 30+
Internet Only
21.7/Each
1/2" NPT x 3/4" Tubing Equivalent Natural Kynar® Male SeriesLock™ Valved Insert - Large
Item 63390
21.7/Each
Save 5% when you buy 5+
Save 10% when you buy 10+
Save 15% when you buy 30+
Internet Only
21.7/Each
1/8" NPT x 1/8" Tubing Equivalent Natural Polypropylene Female SeriesLock™ Valved Coupling - Small
Item 63359
17.72/Each
Save 5% when you buy 5+
Save 10% when you buy 10+
Save 15% when you buy 30+
Internet Only
17.72/Each
1/8" NPT x 3/16" Tubing Equivalent Natural Polypropylene Female SeriesLock™ Valved Coupling - Small
Item 63360
17.72/Each
Save 5% when you buy 5+
Save 10% when you buy 10+
Save 15% when you buy 30+
Internet Only
17.72/Each
1/4" NPT x 1/4" Tubing Equivalent Natural Polypropylene Female SeriesLock™ Valved Coupling - Medium
Item 63361
18.04/Each
Save 5% when you buy 5+
Save 10% when you buy 10+
Save 15% when you buy 30+
Internet Only
18.04/Each
1/4" NPT x 3/8" Tubing Equivalent Natural Polypropylene Female SeriesLock™ Valved Coupling - Medium
Item 63362
18.04/Each
Save 5% when you buy 5+
Save 10% when you buy 10+
Save 15% when you buy 30+
Internet Only
18.04/Each
3/8" NPT x 1/4" Tubing Equivalent Natural Polypropylene Female SeriesLock™ Valved Coupling - Medium
Item 63363
18.04/Each
Save 5% when you buy 5+
Save 10% when you buy 10+
Save 15% when you buy 30+
Internet Only
18.04/Each
3/8" NPT x 3/8" Tubing Equivalent Natural Polypropylene Female SeriesLock™ Valved Coupling - Medium
Item 63364
18.04/Each
Save 5% when you buy 5+
Save 10% when you buy 10+
Save 15% when you buy 30+
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18.04/Each
1/2" NPT x 1/2" Tubing Equivalent Natural Polypropylene Female SeriesLock™ Valved Coupling - Large
Item 63365
20.59/Each
Save 5% when you buy 5+
Save 10% when you buy 10+
Save 15% when you buy 30+
Internet Only
20.59/Each
1/2" NPT x 3/4" Tubing Equivalent Natural Polypropylene Female SeriesLock™ Valved Coupling - Large
Item 63366
20.59/Each
Save 5% when you buy 5+
Save 10% when you buy 10+
Save 15% when you buy 30+
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20.59/Each
1/8" NPT x 1/8" Tubing Equivalent Natural Polypropylene Male SeriesLock™ Valved Insert - Small
Item 63367
13.33/Each
Save 5% when you buy 5+
Save 10% when you buy 10+
Save 15% when you buy 30+
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13.33/Each
1/8" NPT x 3/16" Tubing Equivalent Natural Polypropylene Male SeriesLock™ Valved Insert - Small
Item 63368
13.33/Each
Save 5% when you buy 5+
Save 10% when you buy 10+
Save 15% when you buy 30+
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13.33/Each
1/4" NPT x 1/4" Tubing Equivalent Natural Polypropylene Male SeriesLock™ Valved Insert - Medium
Item 63369
13.76/Each
Save 5% when you buy 5+
Save 10% when you buy 10+
Save 15% when you buy 30+
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13.76/Each
1/4" NPT x 3/8" Tubing Equivalent Natural Polypropylene Male SeriesLock™ Valved Insert - Medium
Item 63370
13.76/Each
Save 5% when you buy 5+
Save 10% when you buy 10+
Save 15% when you buy 30+
Internet Only
13.76/Each
3/8" NPT x 1/4" Tubing Equivalent Natural Polypropylene Male SeriesLock™ Valved Insert - Medium
Item 63371
13.76/Each
Save 5% when you buy 5+
Save 10% when you buy 10+
Save 15% when you buy 30+
Internet Only
13.76/Each
3/8" NPT x 3/8" Tubing Equivalent Natural Polypropylene Male SeriesLock™ Valved Insert - Medium
Item 63372
13.76/Each
Save 5% when you buy 5+
Save 10% when you buy 10+
Save 15% when you buy 30+
Internet Only
13.76/Each
1/2" NPT x 1/2" Tubing Equivalent Natural Polypropylene Male SeriesLock™ Valved Insert - Large
Item 63373
16.66/Each
Save 5% when you buy 5+
Save 10% when you buy 10+
Save 15% when you buy 30+
Internet Only
16.66/Each
1/2" NPT x 3/4" Tubing Equivalent Natural Polypropylene Male SeriesLock™ Valved Insert - Large
Item 63374
16.66/Each
Save 5% when you buy 5+
Save 10% when you buy 10+
Save 15% when you buy 30+
Internet Only
16.66/Each
1/8" NPT x 1/8" Tubing Equivalent Natural Polysulfone Female SeriesLock™ Valved Coupling - Small
Item 63391
22.83/Each
Save 5% when you buy 5+
Save 10% when you buy 10+
Save 15% when you buy 30+
Internet Only
22.83/Each
1/8" NPT x 3/16" Tubing Equivalent Natural Polysulfone Female SeriesLock™ Valved Coupling - Small
Item 63392
22.83/Each
Save 5% when you buy 5+
Save 10% when you buy 10+
Save 15% when you buy 30+
Internet Only
22.83/Each
1/4" NPT x 1/4" Tubing Equivalent Natural Polysulfone Female SeriesLock™ Valved Coupling - Medium
Item 63393
23.99/Each
Save 5% when you buy 5+
Save 10% when you buy 10+
Save 15% when you buy 30+
Internet Only
23.99/Each
1/4" NPT x 3/8" Tubing Equivalent Natural Polysulfone Female SeriesLock™ Valved Coupling - Medium
Item 63394
24.08/Each
Save 5% when you buy 5+
Save 10% when you buy 10+
Save 15% when you buy 30+
Internet Only
24.08/Each
3/8" NPT x 1/4" Tubing Equivalent Natural Polysulfone Female SeriesLock™ Valved Coupling - Medium
Item 63395
23.99/Each
Save 5% when you buy 5+
Save 10% when you buy 10+
Save 15% when you buy 30+
Internet Only
23.99/Each
3/8" NPT x 3/8" Tubing Equivalent Natural Polysulfone Female SeriesLock™ Valved Coupling - Medium
Item 63396
24.08/Each
Save 5% when you buy 5+
Save 10% when you buy 10+
Save 15% when you buy 30+
Internet Only
24.08/Each
1/2" NPT x 1/2" Tubing Equivalent Natural Polysulfone Female SeriesLock™ Valved Coupling - Large
Item 63397
30.21/Each
Save 5% when you buy 5+
Save 10% when you buy 10+
Save 15% when you buy 30+
Internet Only
30.21/Each
1/2" NPT x 3/4" Tubing Equivalent Natural Polysulfone Female SeriesLock™ Valved Coupling - Large
Item 63398
30.57/Each
Save 5% when you buy 5+
Save 10% when you buy 10+
Save 15% when you buy 30+
Internet Only
30.57/Each
1/8" NPT x 1/8" Tubing Equivalent Natural Polysulfone Male SeriesLock™ Valved Insert - Small
Item 63399
15.5/Each
Save 5% when you buy 5+
Save 10% when you buy 10+
Save 15% when you buy 30+
Internet Only
15.5/Each
1/8" NPT x 3/16" Tubing Equivalent Natural Polysulfone Male SeriesLock™ Valved Insert - Small
Item 63400
15.5/Each
Save 5% when you buy 5+
Save 10% when you buy 10+
Save 15% when you buy 30+
Internet Only
15.5/Each
1/4" NPT x 1/4" Tubing Equivalent Natural Polysulfone Male SeriesLock™ Valved Insert - Medium
Item 63401
17.19/Each
Save 5% when you buy 5+
Save 10% when you buy 10+
Save 15% when you buy 30+
Internet Only
17.19/Each
1/4" NPT x 3/8" Tubing Equivalent Natural Polysulfone Male SeriesLock™ Valved Insert - Medium
Item 63402
17.31/Each
Save 5% when you buy 5+
Save 10% when you buy 10+
Save 15% when you buy 30+
Internet Only
17.31/Each
3/8" NPT x 1/4" Tubing Equivalent Natural Polysulfone Male SeriesLock™ Valved Insert - Medium
Item 63403
17.19/Each
Save 5% when you buy 5+
Save 10% when you buy 10+
Save 15% when you buy 30+
Internet Only
17.19/Each
3/8" NPT x 3/8" Tubing Equivalent Natural Polysulfone Male SeriesLock™ Valved Insert - Medium
Item 63404
17.31/Each
Save 5% when you buy 5+
Save 10% when you buy 10+
Save 15% when you buy 30+
Internet Only
17.31/Each
1/2" NPT x 1/2" Tubing Equivalent Natural Polysulfone Male SeriesLock™ Valved Insert - Large
Item 63405
22.29/Each
Save 5% when you buy 5+
Save 10% when you buy 10+
Save 15% when you buy 30+
Internet Only
22.29/Each
1/2" NPT x 3/4" Tubing Equivalent Natural Polysulfone Male SeriesLock™ Valved Insert - Large
Item 63406
22.83/Each
Save 5% when you buy 5+
Save 10% when you buy 10+
Save 15% when you buy 30+
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22.83/Each
1/8" NPT x 1/8" Tubing Equivalent Glass Filled Black Nylon Female SeriesLock™ Valved Coupling - Small
Item 63407
16.95/Each
Save 5% when you buy 5+
Save 10% when you buy 10+
Save 15% when you buy 30+
Internet Only
16.95/Each
1/8" NPT x 3/16" Tubing Equivalent Glass Filled Black Nylon Female SeriesLock™ Valved Coupling - Small
Item 63408
16.95/Each
Save 5% when you buy 5+
Save 10% when you buy 10+
Save 15% when you buy 30+
Internet Only
16.95/Each
1/4" NPT x 1/4" Tubing Equivalent Glass Filled Black Nylon Female SeriesLock™ Valved Coupling - Medium
Item 63409
17.63/Each
Save 5% when you buy 5+
Save 10% when you buy 10+
Save 15% when you buy 30+
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17.63/Each
1/4" NPT x 3/8" Tubing Equivalent Glass Filled Black Nylon Female SeriesLock™ Valved Coupling - Medium
Item 63410
17.63/Each
Save 5% when you buy 5+
Save 10% when you buy 10+
Save 15% when you buy 30+
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17.63/Each
3/8" NPT x 1/4" Tubing Equivalent Glass Filled Black Nylon Female SeriesLock™ Valved Coupling - Medium
Item 63411
17.63/Each
Save 5% when you buy 5+
Save 10% when you buy 10+
Save 15% when you buy 30+
Internet Only
17.63/Each
3/8" NPT x 3/8" Tubing Equivalent Glass Filled Black Nylon Female SeriesLock™ Valved Coupling - Medium
Item 63412
17.63/Each
Save 5% when you buy 5+
Save 10% when you buy 10+
Save 15% when you buy 30+
Internet Only
17.63/Each
1/2" NPT x 1/2" Tubing Equivalent Glass Filled Black Nylon Female SeriesLock™ Valved Coupling - Large
Item 63413
20.4/Each
Save 5% when you buy 5+
Save 10% when you buy 10+
Save 15% when you buy 30+
Internet Only
20.4/Each
1/2" NPT x 3/4" Tubing Equivalent Glass Filled Black Nylon Female SeriesLock™ Valved Coupling - Large
Item 63414
20.55/Each
Save 5% when you buy 5+
Save 10% when you buy 10+
Save 15% when you buy 30+
Internet Only
20.55/Each
1/8" NPT x 1/8" Tubing Equivalent Glass Filled Black Nylon Male SeriesLock™ Valved Insert - Small
Item 63415
12.12/Each
Save 5% when you buy 5+
Save 10% when you buy 10+
Save 15% when you buy 30+
Internet Only
12.12/Each
1/8" NPT x 3/16" Tubing Equivalent Glass Filled Black Nylon Male SeriesLock™ Valved Insert - Small
Item 63416
12.17/Each
Save 5% when you buy 5+
Save 10% when you buy 10+
Save 15% when you buy 30+
Internet Only
12.17/Each
1/4" NPT x 1/4" Tubing Equivalent Glass Filled Black Nylon Male SeriesLock™ Valved Insert - Medium
Item 63417
12.66/Each
Save 5% when you buy 5+
Save 10% when you buy 10+
Save 15% when you buy 30+
Internet Only
12.66/Each
1/4" NPT x 3/8" Tubing Equivalent Glass Filled Black Nylon Male SeriesLock™ Valved Insert - Medium
Item 63418
12.68/Each
Save 5% when you buy 5+
Save 10% when you buy 10+
Save 15% when you buy 30+
Internet Only
12.68/Each
3/8" NPT x 1/4" Tubing Equivalent Glass Filled Black Nylon Male SeriesLock™ Valved Insert - Medium
Item 63419
12.66/Each
Save 5% when you buy 5+
Save 10% when you buy 10+
Save 15% when you buy 30+
Internet Only
12.66/Each
3/8" NPT x 3/8" Tubing Equivalent Glass Filled Black Nylon Male SeriesLock™ Valved Insert - Medium
Item 63420
12.68/Each
Save 5% when you buy 5+
Save 10% when you buy 10+
Save 15% when you buy 30+
Internet Only
12.68/Each
1/2" NPT x 1/2" Tubing Equivalent Glass Filled Black Nylon Male SeriesLock™ Valved Insert - Large
Item 63421
15.76/Each
Save 5% when you buy 5+
Save 10% when you buy 10+
Save 15% when you buy 30+
Internet Only
15.76/Each
1/2" NPT x 3/4" Tubing Equivalent Glass Filled Black Nylon Male SeriesLock™ Valved Insert - Large
Item 63422
15.85/Each
Save 5% when you buy 5+
Save 10% when you buy 10+
Save 15% when you buy 30+
Internet Only
15.85/Each